Smoking history and emphysema in asthma–COPD overlap

Smoking history and emphysema in asthma–COPD overlap

Background Emphysema is a distinct feature for classifying COPD, and smoking history (≥10 pack-years) is one of several newly proposed criteria for asthma-COPD overlap (ACO). We studied whether or not a smoking history (≥10 pack-years) and emphysema are useful markers for classifying ACO and differentiating it from asthma with chronic airflow obstruction (CAO). Methods We retrospectively stud...

Cigarette smoking, asthma, and emphysema.

1 Light RW, Cheng DS, Lee YC, et al. A single intrapleural injection of transforming growth factor(2) produces an excellent pleurodesis in rabbits. Am J Respir Crit Care Med 2000; 162:98–104 2 Lee YC, Lane KB, Parker RE, et al. Transforming growth factor (2) (TGF (2)) produces effective pleurodesis in sheep with no systemic complications. Thorax 2000; 55:1058–1062 3 Gary Lee YC, Teixeira LR, De...

Dependence of the incidence of emphysema on smoking history, age, and sex.

Emphysema and secondary pneumothorax in young adults smoking cannabis.

BACKGROUND We observed a remarkable increase in the number of young patients who presented with lung emphysema and secondary spontaneous pneumothorax (SSP) at our institution for over a period of 30 months; most of them have a common history of marijuana abuse. STUDY DESIGN Retrospective case series. METHODS Seventeen young patients presented with spontaneous pneumothorax with bullous lung ...

Microscopic emphysema in relation to age and smoking habit.

BACKGROUND The increases in airspace size within the human lung associated with microscopic emphysema can be assessed by measuring the airspace wall surface area per unit volume of lung tissue (AWUV). In a previous study the limits of normality of AWUV with age were estimated in lifelong non-smokers by the 95% prediction limits of the regression line for these variables. The aims of this study ...